Biochemical Sensitivity of Surface Plasmon Resonance Sensors

Biochemical sensors based on surface plasmon resonance (SPR) are highly efficient tools for label free chemical detection and for the investigation of real time biomolecular interactions. This flexible, powerful and highly sensitive technique is widely used for rapid detection in medical and biological fields. The current research work focus on the surface plasmon resonance of the metal’s gold and copper through simulation analysis. The theoretical analysis was based on Fresnel’s equations of electromagnetic waves that describe the behaviour of light waves when they encounter an interface between two media with different refractive indices. The propagating surface plasmon waves are analysed on the planar structure on prism based Kretschmann Raether configuration. The angular scanning method of SPR detection was employed in this process. The reflected light intensity was measured for an angular range of 0^o to 90^o. Also, SPR bio sensitivity was studied by employing a simulated sugar solution environment to the metal surface. The detection sensitivity of SPR based sensors are revealed through this work.